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KMID : 0388420000100010127
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Konkuk Journal of Medical Sciences
2000 Volume.10 No. 1 p.127 ~ p.136
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A Case of Chronic Eosinophilic Pneumonia, associated with Sudden Diffuse Pneumonic Consolidations
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Youn Ho-Sang
Yoo Kwang-Ha
Jeon Hae-Jeong
Lee Su-In
Jin Chun-Jo
Chung Sang-Man
Lee Sang-Yeup
Kim Seon-Doo
Lee Soon-Jae
Lee Kil-Do
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Abstract
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Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP ,although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator.
We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.
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KEYWORD
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chronic eosinophilic pneumonia, bilateral pleural effusion, sudden course
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